7.Syphilis
This rather rare sexually transmitted disease (STD) can cause problems with your lungs. Symptoms include a skin rash, fatigue, headache, and muscle pain. In some people, it also causes extra fliud to build up around your lungs. This can cause sharp chest pain and a cough with mucus. Antibiotics will help clear it up.
8.Asthma
Chest tightness is a symptom of this, along with coughing, wheezing, and struggling to catch your breath. It can be triggered by many different things, from dust and pet hair to certain things in food or physical activity. Medication can help keep your airways open and help when symptoms flare up.